Mr Hemant Sheth

Mr Sheth is a consultant laparoscopic UGI & Hepatobiliary surgeon. His practice covers a wide range of problems, including issues with the oesophagus, stomach, liver, gall bladder, and pancreas. He has a particular interest in anti-reflux surgery (fundoplication), diaphragmatic hernia surgery, and laparoscopic cholecystectomy including bile duct exploration. He also offers diagnostic UGI endoscopy and specializes in laparoscopic management of inguinal, epigastric, umbilical, ventral, and incisional hernia surgery.

He studied medicine in Mumbai, India and qualified as a surgeon in 1994. Following FRCS in 1996, he began training in the UK. In 1999, he joined the Royal Free Hospital Liver Unit to train in hepatobiliary surgery and liver transplantation, and registered for a postgraduate research degree from University College London. He joined the Northeast London surgical training scheme for General Surgery in 2004, and acquired specialist training in UGI and hepatobiliary surgery, working in various liver units in the region including Barts & The London and Royal Free.

Upon completion of his training in 2009, he joined Addenbrookes Hospital in Cambridge for further specialist training in laparoscopic hepatobiliary surgery . He was awarded the MD (research) degree from University College London for my thesis titled 'Therapeutic Modulation Of Liver Ischaemia Reperfusion Injury'.

He is currently working as consultant UGI, Hepatobiliary & laparoscopic surgeon at Ealing and London Northwest Healthcare Trust. He has been awarded clinical excellence awards in his current job. He has also been appointed as the Surgical Tutor for the trust and Clinical lead for the department of surgery at Ealing site.

Clinical Interests

Qualification and Professional Memberships

Qualifications

Clinical Professor 2023

FRCS ( RCS Eng) RCS England 2009

MD (Research) University College London 2010

FRCS( RCS Glagow) RCS Glasgow 1996

MS ( General Surgery) TNMC Mumbai India 1994

MBBS TNMC Mumbai India 1990

Professional Memberships

GMC registration

Reference number 4567912

Professional bodies (positions held - last 3 yrs)

Surgical Tutor RCS England 2012

Member of AUGIS AUGIS 2018

Faculty for the Intermediate Laparoscopic Skills Course for RCS England

Affiliations / memberships

AUGIS

RCS England

EAHPBA

IHPBA

Research and Publications

Splenectomy For haematological disorders

Accepted by the university of Bombay for MS (GenSurg.) in January 1994

Splenectomy plays a major therapeutic role in the composite management of various haematological disorders. Splenectomy was particularly useful for disorders like Hereditary Spherocytosis and ITP, while the responses to disorders like Thalassemia, Portal hypertension, chronic Leukaemia’s was intermediate to poor. The overall morbidity & mortality is low.

Therapeutic Modulation of Liver Ischaemia Reperfusion Injury

Submitted for MD (Research), University College London

Ischaemia reperfusion injury is one of the causes of primary graft dysfunction following liver transplantation. Kupffer cells activation is the key event, which initiates liver ischaemia reperfusion injury. This leads to activation of the cytokine cascade and generation of free radicals, which further aggravates the reperfusion injury. Blockade of Kupffer cells and free radical initiated injury with Glycine a non-essential amino acid and N-acetylcysteine a free radical scavenger may ameliorate this injury and improve graft function.

The weekend effect - ow can it be mitigated? Introduction of a consultant-delivered emergency general surgical service

Operative data was analysed from a prospectively collected database over 5-years. Primary outcome measures were 30-day all-cause mortality and Clavien-Dindo class ≧ 2 morbidity. Secondary outcomes included time from admission to diagnostic imaging and time to surgery, post-operative length of stay and requirement for Intensive Care Unit admission.

Peer-reviewed publications

The Diagnostic Utility and Clinical Impact of After-Hours CT Scans of the Abdomen and Pelvis Investigating Abdominal Pain; Scientific World Journal Volume 2017, Monil Karia, Matthew Seager, Akkib Rafique, and Hemant Sheth; Article ID 4028352, 6 pages,
https://doi.org/10.1155/2017/4028352

Non-haemorrhagic, bilateral adrenal infarction in a patient with antiphospholipid syndrome along with lupus myocarditis ;Nicholas Marinus Batt, Dean Malik, Miranda Harvie, Hemant Sheth; BMJ Case Reports 2016:published online 20 July 2016, doi:10.1136/bcr-2016-216364

Primary Gallbladder Lymphoma in a Male Patient with No Risk Factors Detected Incidentally by CT Colonography; Monil Karia , Grigorios Mitsopoulos, Ketan Patel, Akkib Rafique, and Hemant Sheth; Case Rep Surg. 2015; 2015: 813708. Published online 2015 Oct 26. doi: 10.1155/2015/813708

Unemployment, public-sector healthcare spending and stomach cancer mortality in the European Union, 1981-2009. Maruthappu M, Painter A, Watkins J, Williams C, Ali R, Zeltner T, Faiz O, Sheth H. Eur J Gastroenterol Hepatol. 2014 Nov;26(11):1222-7. doi: 10.1097/MEG.0000000000000201

Vancomycin-induced thrombocytopaenia in a patient with severe pancreatitis; Rowland S, Rankin I, Sheth H: BMJ Case Reports 2013; doi:10.1136/bcr2013200830.

Spontaneous Intraperitoneal Rupture of a Hepatic Hydatid Cyst with Subsequent Anaphylaxis: A Case Report; Tinsley B, Abbara, A, Kadaba R, Sandhu G, Sheth H Case Reports in Hepatology;Volume 2013 (2013), Article ID 320418, 4 pages
http://dx.doi.org/10.1155/2013/320418

Hepatic Portal Venous Gas: Comparison of Two Cases; Rankin I and Sheth H: Case Reports in Surgery; Volume 2013 (2013), Article ID 637951, 5 pages
http://dx.doi.org/10.1155/2013/637951

Hepatic Portal Venous Gas due to Acute on Chronic Gastric Ischaemia; Misro A & Sheth H: Eur J Surg Sci 2012;3(2):69-72;

A case of emphysematous pyelonephritis. Rowland SP, Sheth H; ANZ J Surg. 2013 Oct 28. doi: 10.1111/ans.12224. [Epub ahead of print] No abstract available.

An intraoperative cholangiogram: unusual anatomy. Rowland SP and Sheth H ; BMJ. 2013 Sep 13;347:f5238. doi: 10.1136/bmj.f5238.

Endoscopic biopsy on patients taking antiplatelet agents: How much do we follow BSG, ASGE or ESGE guidelines? Misro AK, Pal A, Sheth H, ; Indian J Gastroenterol. 2013 Oct 2. [Epub ahead of print] No abstract available. PMID:24085709

Glycine reduces liver warm ischaemia reperfusion injury by improving the hepatic microcirculation and enhancing mitochondrial activity; Sheth H, Hafez T, Glantzounis G, Sales K, Seifalian A, Fuller B, Davidson B R Journal of Hepatology and Gastroenterology 2010.

Methods of vascular occlusion for elective liver resections; Gurusamy KS, Sheth H, Kumar Y, Sharma D, Davidson BR COCHRANE DATABASE SYST REV. 2009 Jan 21;(1):CD007632.

Acute limb ischemia caused by femoral arterial line induces remote liver injury in a rabbit model of liver ischemia/reperfusion injury; Glantzounis GK, Sheth H, Thompson C, Hafez TS, Kanoria S, Pamecha V, Davies S, Mikhailidis DP, Seifalian AM, Davidson BR Angiology. 2009 Oct-Nov; 60(5):554-61. Epub

Glycine Protects Bile Physiology and Biliary-Specific Liver Cell Metabolism from Ischemia-Reperfusion Injury; a 1H NMR Study: Hafez T, Sheth H, Glantzounis G, Parkes H, Seifalian A, Fuller B, Davidson B; Cell Preservation Technology 6:173–180 (2008).

Fishbone perforation mimicking a gastric intramural tumour: a case report; Bajwa A, Sheth H, Hughes F ; Grand Rounds, Vol 7, pg 42-44, 2007.

Midgut malrotation as a rare cause of chronic abdominal pain: a case report and review of literature: Bajwa A, Sheth H, Hughes F ; Grand Rounds, Vol. 7, pg 6769, 11 September 2007.

Formation and role of plasma S-nitrosothiols in liver ischaemia-reperfusion injury; Glantzounis G, Rocks S A, Sheth H, Knight I, Salacinski H J, Davidson B R, P G Winyard P G, Seifalian A M; Free Radic Biol Med. 42(6): 882-92; 15 March 2007

N- Acetylcysteine ameliorates the late phase of liver ischaemia/reperfusion injury in the rabbit with hepatic steatosis: , Fusai G,Glantzounis G, Hafez T, Yang W, Quaglia A, Sheth H, Kanoria S, Parkes H, Seifalian A, Davidson B R; Clin. Sci (Lond); 2005; 109:465-73.

Radioisptope bone Scans in the Preoperative Staging of Hepato-pancreato biliary Cancer: Sheth H, Javed S S, Hilson A J W, Buscombe J R, Davidson B R British J of Surgery; 92 (2): 203-7. February 2005